2021-09-30

Department of Obstetrics, Gynecology, and Perinatology, Hamedan University of Medical Science, Hamedan, Iran.; Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.; Neuroscience Research Center, Guilan University of Medical Sciences, Rasht, Iran.; Department of Virology, Faculty of Medicine, Iran University of Medical Science, Tehran, Iran.; Department of Pediatrics, Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Department of Obstetrics, Gynecology, and Perinatology, Hamedan University of Medical Science, Hamedan, Iran.; Department of Radiology, Hashemi Rafsanjani Hospital, North Khorasan University of Medical Sciences, Shirvan, Iran.; Department of Biological Science, University of Calgary, Calgary, Alberta, Canada.; John B. Little Center for Radiation Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Virology, Faculty of Medicine, Iran University of Medical Science, Tehran, Iran.; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Center of Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

In a large-scale study, 128176 non-pregnant patients (228 studies) and 10000 pregnant patients (121 studies) confirmed COVID-19 cases included in this Meta-Analysis. The mean (confidence interval [CI]) of age and gestational age of admission (GA) in pregnant women was 33 (28-37) years old and 36 (34-37) weeks, respectively. Pregnant women show the same manifestations of COVID-19 as non-pregnant adult patients. Fever (pregnant: 75.5%; non-pregnant: 74%) and cough (pregnant: 48.5%; non-pregnant: 53.5%) are the most common symptoms in both groups followed by myalgia (26.5%) and chill (25%) in pregnant and dysgeusia (27%) and fatigue (26.5%) in non-pregnant patients. Pregnant women are less probable to show cough (odds ratio [OR] 0.7; 95% CI 0.67-0.75), fatigue (OR: 0.58; CI: 0.54-0.61), sore throat (OR: 0.66; CI: 0.61-0.7), headache (OR: 0.55; CI: 0.55-0.58) and diarrhea (OR: 0.46; CI: 0.4-0.51) than non-pregnant adult patients. The most common imaging found in pregnant women is