共检索2条数据Total:2
2021-12-02
Medicine/PACC, Columbia University Irving Medical Center, New York, New York, USA.; Medicine/PACC, Columbia University Irving Medical Center, New York, New York, USA.; Medicine/PACC, Columbia University Irving Medical Center, New York, New York, USA.; Radiology, Columbia University Medical Center, New York, New York, USA.; Radiology, Columbia University Medical Center, New York, New York, USA.; Radiology, Internal Medicine, and Biomedical Engineering, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.; Biostatistics, Columbia University Medical Center, New York, New York, USA.; Medicine/PACC, Columbia University Irving Medical Center, New York, New York, USA.; Medicine/PACC, Columbia University Irving Medical Center, New York, New York, USA ckg2116@cumc.columbia.edu.; Institute of Genomic Medicine, Center for Precision Medicine and Genomics, Columbia University Irving Medical Center, New York, NY, USA.
The risk factors for development of fibrotic-like radiographic abnormalities after severe COVID-19 are incompletely described and the extent to which CT findings correlate with symptoms and physical function after hospitalisation remains unclear. At 4 months after hospitalisation, fibrotic-like patterns were more common in those who underwent mechanical ventilation (72%) than in those who did not (20%). We demonstrate that severity of initial illness, duration of mechanical ventilation, lactate dehydrogenase on admission and leucocyte telomere length are independent risk factors for fibrotic-like radiographic abnormalities. These fibrotic-like changes correlate with lung function, cough and measures of frailty, but not with dyspnoea.CI - © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
2021-04-26
Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032. Electronic address: kmc9020@nyp.org.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.
BACKGROUND: COVID-19 commonly presents with upper respiratory symptoms; however, studies have shown that SARS-CoV-2 infection affects multiple organ systems. Here, we review the pathophysiology and imaging characteristics of SARS-CoV-2 infection in organ systems throughout the body and explore commonalities. OBJECTIVE: Familiarity with the underlying pathophysiology and imaging characteristics is essential for the radiologist to recognize these findings in patients with COVID-19 infection. Though pulmonary findings are the most prevalent presentation, COVID-19 may have multiple manifestations and recognition of the extrapulmonary manifestations is especially important because of the potential serious and long-term effects of COVID-19 on multiple organ systems.CI - Copyright © 2021. Published by Elsevier Inc.