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Geisinger Commonwealth School of Medicine, Scranton, PA, USA.; Department of Public Health, Icahn School of Medicine At Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, USA. pmalik.ma@gmail.com.; Drexel University College of Medicine, Philadelphia, PA, USA.; Ascension Via Christi Hospital, Manhattan, KS, USA.; St Mary Medical Center, Langhorne, PA, USA.; Guthrie Robert Packer Hospital, Sayre, PA, USA.; Department of Public Health, Icahn School of Medicine At Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, USA.; University of Illinois College of Medicine Peoria, Champaign, IL, USA.; Ascension Providence Hospital/Michigan State University College of Human Medicine, East Lansing, USA.; University of Illinois at Chicago, Chicago, IL, USA.; Temple University, Philadelphia, PA, USA.; Department of Public Health, Icahn School of Medicine At Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, USA.; New York Medical College, Hawthorne, NY, USA.; College of Medicine, Central Michigan University, Saginaw, MI, USA.

We aimed to identify prevalence and association of comorbid chronic kidney disease (CKD), acute kidney injury (AKI) and utilization prevalence of continuous renal replacement therapy (CRRT) in COVID-19-hospitalized patients as a function of severity status. With the ongoing struggle across the globe to combat COVID-19 disease, published literature has described the role of kidney disease in COVID-19 patients based on single/multicenter experiences across the globe. We extracted data from observational studies describing comorbid CKD, AKI and CRRT and outcomes and severity of COVID-19-hospitalized patients from December 1, 2019-August 20, 2020 following PRISMA guidelines. Severity of COVID-19 includes intensive care unit admission, oxygen saturation < 90%, invasive mechanical ventilation utilization, in-hospital admission and mortality. Meta-analysis was performed using a random-effects model to calculate pooled estimates, and forest plots were created. In total, 29 studies with 15,017

2021-04-26

Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032. Electronic address: kmc9020@nyp.org.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.; Department of Radiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032.

BACKGROUND: COVID-19 commonly presents with upper respiratory symptoms; however, studies have shown that SARS-CoV-2 infection affects multiple organ systems. Here, we review the pathophysiology and imaging characteristics of SARS-CoV-2 infection in organ systems throughout the body and explore commonalities. OBJECTIVE: Familiarity with the underlying pathophysiology and imaging characteristics is essential for the radiologist to recognize these findings in patients with COVID-19 infection. Though pulmonary findings are the most prevalent presentation, COVID-19 may have multiple manifestations and recognition of the extrapulmonary manifestations is especially important because of the potential serious and long-term effects of COVID-19 on multiple organ systems.CI - Copyright © 2021. Published by Elsevier Inc.