共检索20条数据Total:20
2021-07-27
College of Nursing and Brain Korea 21 FOUR Project, Yonsei University, Seoul, Korea.; College of Nursing and Mo-Im Kim Nursing Research Institute, Yonsei University, Seoul, Korea.; College of Nursing, Yonsei University, Seoul, Korea.
The coronavirus pandemic highlights the urgent need for increased support related to mental health concerns. This study aimed to synthesize the findings of empirical studies reporting the post-traumatic stress symptoms in the general population during the coronavirus pandemic. Whittemore and Knafl's (Journal of Advanced Nursing, 52, 546, 2005) integrative review methodology was used to analyse and synthesize the peer-reviewed studies. Five electronic databases, PubMed, CINAHL, PsychINFO, Cochrane and Google Scholar were searched using terms related to the coronavirus pandemic and post-traumatic stress symptoms. The quality of the studies was screened and evaluated using the Mixed Methods Appraisal Tool. The sample size of the 16 studies included in this review ranged from 41 to 3480 participants, with a total of 18 039 participants. The majority of the participants' ages ranged from 30 to 39 years, and 57% of the participants were female. The following factors related to
2021-01-03
Institute of Health Insurance Research, National Health Insurance Service, Wonju, Korea.; Department of Communication and Media, Ewha Womans University, Seoul, Korea.; Institute of Health and Environment, Seoul National University, Seoul, Korea. loshjeve@snu.ac.kr.
With the rapid spread of coronavirus disease 2019 (COVID-19), a particularly sharp increase in the number of confirmed cases in Daegu and Gyeongbuk regions at the end of February, Korea faced an unprecedented shortage of medical resources, including hospital beds. To cope with this shortage, the government introduced a severity scoring system for patients with COVID-19 and designed a new type of quarantine facility for treating and isolating patients with mild symptoms out of the hospital, namely, the Residential Treatment Center (RTC). A patient with mild symptoms was immediately isolated in the RTC and continuously monitored to detect changes in symptoms. If the symptoms aggravate, the patient was transferred to a hospital. RTCs were designed by creating a quarantine environment in existing lodging facilities capable of accommodating > 100 individuals. The facilities were entirely divided into a clean zone (working area) and contaminated zone (patient zone), separating the space
2021-08-24
Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.; Department of Cardiology, School of Medicine & Institute of Medical Science, Keimyung University, Daegu, Korea.; Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea. khyungseop@dsmc.or.kr.; Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.; Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.; Department of Radiology, Keimyung University Dongsan Medical Center, Daegu, Korea.
Increasing rates of coronavirus disease 2019 (COVID-19) vaccination coverage will result in more vaccine-related side effects, including acute myocarditis. In Korea, we present a 24-year-old male with acute myocarditis following COVID-19 vaccination (BNT162b2). His chest pain developed the day after vaccination and cardiac biomarkers were elevated. Echocardiography showed minimal pericardial effusion but normal myocardial contractility. Electrocardiography revealed diffuse ST elevation in lead II, and V2-5. Cardiac magnetic resonance images showed the high signal intensity of T2- short tau inversion recovery image, the high value of T2 mapping sequence, and late gadolinium enhancement in basal inferior and inferolateral wall. It was presumed that COVID-19 mRNA vaccination was probably responsible for acute myocarditis. Clinical course of the patient was favorable and he was discharged without any adverse event.CI - © 2021 The Korean Academy of Medical Sciences.
Research Information Technology, College of Medicine, Ohio State University, 1585 Neil Ave, Columbus, OH, 43210, USA.; 1Department of Biomedical Informatics, The Ohio State University, Columbus, OH, 43210, USA.; The Grainger College of Engineering, The University of Illinois-Urbana-Champaign, Urbana and Champaign, Champaign, IL, 61801, USA.; 1Department of Biomedical Informatics, The Ohio State University, Columbus, OH, 43210, USA.; 1Department of Biomedical Informatics, The Ohio State University, Columbus, OH, 43210, USA. lijun.cheng@osumc.edu.
Lots of cell death initiator and effector molecules, signalling pathways and subcellular sites have been identified as key mediators in both cell death processes in cancer. The XDeathDB visualization platform provides a comprehensive cell death and their crosstalk resource for deciphering the signaling network organization of interactions among different cell death modes associated with 1461 cancer types and COVID-19, with an aim to understand the molecular mechanisms of physiological cell death in disease and facilitate systems-oriented novel drug discovery in inducing cell deaths properly. Apoptosis, autosis, efferocytosis, ferroptosis, immunogenic cell death, intrinsic apoptosis, lysosomal cell death, mitotic cell death, mitochondrial permeability transition, necroptosis, parthanatos, and pyroptosis related to 12 cell deaths and their crosstalk can be observed systematically by the platform. Big data for cell death gene-disease associations, gene-cell death pathway associations
2021-11-17
Scool of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; School of Health Sciences, Faculty of Environmental & Life Sciences, University of Southampton, Southampton, UK.; School of Electronics and Computer Science, University of Southampton, Southampton, UK.; School of Health Sciences, Faculty of Environmental & Life Sciences, University of Southampton, Southampton, UK.; School of Health Sciences, Faculty of Environmental & Life Sciences, University of Southampton, Southampton, UK.; Scool of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK Y.Cheong@soton.ac.uk.; Complete Fertility Southampton, Princess Anne Hospital, Southampton, UK.
INTRODUCTION: Black, Asian and minority ethnic (BAME) people are disproportionately affected by COVID-19. Respiratory protective equipment (RPE) has conventionally been developed for a predominantly white male population that does not represent the healthcare workforce. The literature was reviewed to determine the protection offered to female and BAME users. METHODS: Five databases were searched. Eligible studies related to respirator fit in the context of anthropometrics, gender and ethnicity. Meta-analysis was performed for gender-based anthropometric differences. A priori protocol registration was not performed. RESULTS: 32 studies were included and anthropometric data was extracted from 15 studies. Meta-analysis revealed 14 anthropometric measurements were significantly smaller for females. Mean differences ranged from 0.37 mm to 22.05 mm. Gender-based anthropometric differences did not always translate to lower fit factor scores, with 12 studies reporting worse performance and
2021-06-24
Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.; Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.; Department of Center of Biomedical Data Science, Yonsei University Wonju College of Medicine, Wonju, Korea.; Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.; Department of Emergency Medicine, Seoul National University Hospital, Seoul, Korea.; National Emergency Medical Center, National Medical Center, Seoul, Korea. ro.youngsun@gmail.com.; Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. ohkim@yonsei.ac.kr.
PURPOSE: Severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19), has spread worldwide. Global health systems, including emergency medical systems, are suffering from a lack of medical resources. Using a method for classifying patients visiting the emergency department (ED), we aimed to investigate trends in emergency medical system usage during the COVID-19 epidemic in Korea. MATERIALS AND METHODS: This retrospective observational study included patients who visited emergency medical institutions registered with the National Emergency Department Information System database from January 1, 2017 to May 31, 2020. The primary outcome was identification of changes in the distribution of patients visiting the ED according to the type of emergency medical institution. The secondary outcome was a detailed comparison of Korean Triage and Acuity Scale (KTAS) levels and patient distributions before and during the infectious disaster crisis period.
2021-06-03
Department of Public Health Sciences, Institute of Health and Environment and Graduate School of Public Health, Seoul National University, Seoul 08826, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.; Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang-si 10326, Korea.; Data management and Statistics Institute, Dongguk University Ilsan Hospital, Goyang-si 10326, Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.; Kidney Research Institute, Seoul National University Hospital, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul 07061, Korea.; Department of Public Health Sciences, Institute of Health and Environment and Graduate School of Public Health, Seoul National University, Seoul 08826, Korea.
Certain underlying diseases such as diabetic mellitus and hypertension are a risk factor for the severity and mortality of coronavirus disease (COVID-19) patients. Furthermore, both angiotensin converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARBs) are controversial at role in the process of COVID-19 cases. The aim of the study was to investigate whether underlying diseases and taking ACEi/ARBs, affect the duration of hospitalization and mortality in patients with confirmed COVID-19. Medical usage claims data for the past three years until 15 May 2020, from the "CORONA-19 International Cooperation Research" project was used. We analyzed the medical insurance claims data for all 7590 coronavirus (COVID-19) patients confirmed by RT-PCR tests nationwide up to 15 May 2020. Among the comorbidities, a history of hypertension (hazard ratio [HR], 1.51; 95% confidence interval [CI], 1.056-2.158) and diabetes (HR, 1.867; 95% CI, 1.408-2.475) were associated
2021-12-07
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea; Gwang-ju Mental Health Commission, Gwangju, Republic of Korea.; Gwang-ju Mental Health Commission, Gwangju, Republic of Korea.; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.; Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea; Gwang-ju Mental Health Commission, Gwangju, Republic of Korea. Electronic address: swkim@chonnam.ac.kr.
BACKGROUND: During the COVID-19 pandemic, nurses might experience added emotional stress. This study examined the relationship between gratitude and psychological stress to explore effective psychological support among nurses. METHODS: A cross-sectional survey assessed the level of psychological distress in 646 nurses in Gwangju, South Korea, using the Perceived Stress Scale-10 (PSS-10), Gratitude Questionnaire-6 (K-GQ-6), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Maslach Burnout Inventory-General Survey (MBI-GS). Sociodemographic factors and COVID-19-related experiences were also examined. A linear regression model was used to determine the factors influencing perceived stress. RESULTS: The mean PSS-10 score was 19.0 ± 4.4. Linear regression analyses revealed that the MBI-GS-Exhaustion, PHQ-9, and GAD-7 scores were positively associated with perceived stress, while the MBI-GS-Professional efficacy score was inversely associated with perceived
2021-08-24
Division of Infectious Diseases, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Neurosurgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Division of Hematology/Oncology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Division of Hematology/Oncology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Neurosurgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Neurosurgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Division of Infectious Diseases, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Neurosurgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Neurosurgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. operatua@gmail.com.
Vaccination with an adenoviral vector vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can result in the rare development of thrombosis with thrombocytopenia mediated by platelet-activating antibodies against platelet factor 4 (PF4). This is a life-threating condition that may be accompanied by bleeding due to thrombocytopenia with thrombosis of the cerebral venous sinus or splanchnic vein. Herein, we describe the first fatal case of thrombosis with thrombocytopenia syndrome in Korea, presenting with intracranial hemorrhage caused by cerebral venous sinus thrombosis. A 33-year-old Korean man received the first dose of the ChAdOx1 nCoV-19 vaccination. He developed severe headache with vomiting 9 days after the vaccination. Twelve days after vaccination, he was admitted to the hospital with neurological symptoms and was diagnosed with cerebral venous sinus thrombosis, which was accompanied by intracranial hemorrhage. Thrombocytopenia and D-dimer elevation
Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA. anz4001@med.cornell.edu.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, USA.; Carle Illinois College of Medicine, Champaign, IL, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Laboratory of Bacteriology, The Rockefeller University, New York, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.; Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA.
BACKGROUND: Laboratory parameters and the associated clinical outcomes have been an area of focus in COVID-19 research globally. PURPOSE: We performed a scoping review to synthesize laboratory values described in the literature and their associations with mortality and disease severity. METHODS: We identified all primary studies involving laboratory values with clinical outcomes as a primary endpoint by performing data searches in various systematic review databases until 10th August, 2020. Two reviewers independently reviewed all abstracts (13,568 articles) and full text (1126 articles) data. A total of 529 studies involving 165,020 patients from 28 different countries were included. Investigation of the number of studies and patients from a geographical perspective showed that the majority of published literature from January-March 2020 to April-June 2020 was from Asia, though there was a temporal shift in published studies to Europe and the Americas. For each laboratory value, the