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College of Medical Information Engineering, Chengdu University of Traditional Chinese Medicine, Chengdu, China; School of Public Health, Chengdu Medical College, Chengdu, China.; College of Medical Information Engineering, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Public Health, Lanzhou University, Lanzhou, China.; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; WHO Collaborating Centre for Guideline Implementation and Knowledge Translation, Lanzhou, China; GIN (Guidelines International Network) Asia, Lanzhou, China; Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou University, Lanzhou, China.; The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.; School of Public Health, Lanzhou University, Lanzhou, China.; School of Public Health, Chengdu Medical College, Chengdu, China.; School of Clinical Medicine, Chengdu Medical College, Chengdu, China.; School of Public Health, Chengdu Medical College, Chengdu, China.; The Second School of Clinical Medicine, Chongqing Medical University, Chongqing, China.; Department of Pediatric, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.; School of Pharmacy, Chengdu Medical College, Chengdu, China.; Department of Emergency Medicine, The General Hospital of Western Theater Command of PLA, Chengdu, China.; College of Medical Information Engineering, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Public Health, Chengdu Medical College, Chengdu, China.CN - COVID-19 Evidence and Recommendations Working Group
BACKGROUND: Corona virus disease 2019 (COVID-19) showed a significant difference in case fatality rate between different regions at the early stage of the epidemic. In addition to the well-known factors such as age structure, detection efficiency, and race, there was also a possibility that medical resource shortage caused the increase of the case fatality rate in some regions. METHODS: Medline, Cochrane Library, Embase, Web of Science, CBM, CNKI, and Wan fang of identified articles were searched through 29 June 2020. Cohort studies and case series with duration information on COVID-19 patients were included. Two independent reviewers extracted the data using a standardized data collection form and assessed the risk of bias. Data were synthesized through description and analysis methods including a meta-analysis. RESULTS: A total of 109 articles were retrieved. The time interval from onset to the first medical visit of COVID-19 patients in China was 3.38±1.55 days (corresponding