2021-11-03

Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University School of Medicine, Morgantown, WV, 26506, USA. Shitiz.sriwastava@hsc.wvu.edu.; West Virginia Clinical and Translational Science Institute, Morgantown, WV, USA. Shitiz.sriwastava@hsc.wvu.edu.; Department of Neurology, Wayne State University, Detroit, MI, USA. Shitiz.sriwastava@hsc.wvu.edu.; Deaprtment of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Army College of Medical Sciences, New Delhi, India.; Department of Neurology, Berkeley Medical Center, West Virginia University, Martinsburg, WV, USA.; Department of Biostatistics, West Virginia University, Morgantown, WV, USA.; Department of Biostatistics, West Virginia University, Morgantown, WV, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.; West Virginia Clinical and Translational Science Institute, Morgantown, WV, USA.; Nepal Health Research Council, Kathmandu, Nepal.; Department of Neuropsychiatry, Minia University, Minia, Egypt.; Department of Neurology, Wayne State University, Detroit, MI, USA.; Department of Biochemistry, Microbiology and Immunology, Wayne State University, Detroit, MI, USA.

BACKGROUND: The literature on neurological manifestations in COVID-19 patients has been rapidly increasing with the pandemic. However, data on CNS inflammatory disorders in COVID-19 are still evolving. We performed a literature review of CNS inflammatory disorders associated with coronavirus disease-2019 (COVID-19). METHODS: We screened all articles resulting from a search of PubMed, Google Scholar and Scopus, using the keywords; "SARS-CoV-2 and neurological complication", "SARS-CoV-2 and CNS Complication" looking for reports of transverse myelitis, longitudinally extensive transverse myelitis, neuromyelitis optica, myelitis, Myelin Oligodendrocyte Glycoprotein Antibody Disorder (MOGAD), Acute Disseminated Encephalomyelitis (ADEM), Acute Hemorrhagic Necrotizing Encephalitis/Acute Hemorrhagic Leukoencephalitis (AHNE/AHLE), Cytotoxic lesion of the Corpus Callosum/Mild Encephalopathy Reversible Splenium Lesion(CLOCC/MERS) and Optic neuritis published between December 01, 2019 and March